With the scare of batches being contaminated so many people hesitated to go out & get their shots,& now there is a shortage!
Flu Shot Shortage Highlights U.S. Crisis -Officials
Fri Oct 8, 2004 02:58 PM ET
By Maggie Fox, Health and Science Correspondent
WASHINGTON (Reuters) - Concerned health officials began investigating on Friday what went wrong at a British vaccine plant where half the U.S. flu shots were made, and called on more companies to get into the vaccine business.
The officials said the closure of Chiron Corp.'s Liverpool facility was only the latest in a long line of vaccine disasters to hit the United States and warned things will only get worse if companies are not somehow lured back into making vaccines.
"This shortage is a call to action," Centers for Disease Control and Prevention director Dr. Julie Gerberding told reporters after a meeting of the House Committee on Government Reform, called to investigate the issue.
Chiron, based in Emeryville, California, was supposed to supply 48 million doses of U.S. flu vaccine for this year. The company now says it cannot ship any, although U.S. officials hope some may be salvaged.
Chiron shares lost 87 cents, or 2.3 percent, to $35.66 in early afternoon trading on Nasdaq.
Chiron had earlier said that several lots, accounting for a few million doses, were contaminated with a bacteria called Serratia. The company said it had the problem under control but on Tuesday Britain's Medicines and Healthcare Products Regulatory Agency revoked its license for the vaccine, citing plant-wide problems.
U.S. Food and Drug Administration officials met with their British counterparts on Thursday and were in Liverpool with Chiron on Friday, Acting FDA chief Dr. Lester Crawford said.
Some of Chiron's vaccine may be usable, he told the hearing. "It is not possible to say if any of them are salvageable at this point," Crawford said.
"I have to present to you a pessimistic view about whether we can clear any of those."
Gerberding and other health officials have been warning for years that too few companies make vaccine and too few Americans get the flu shots. Flu kills 36,000 Americans in an average year and lands 200,000 in the hospital.
But the vaccine-making business is risky, said Dr. Tony Fauci, head of the National Institute of Allergy and Infectious Diseases. Influenza vaccine, which must be reformulated each year to match mutating strains and takes months to produce, is the worst.
A flu shot, good for year, also costs $10, versus $1,600 for a year's supply of a brand-name cholesterol drug, he said.
The CDC could contract for and buy more vaccine, but taxpayers would have to accept that it may be wasted if demand drops, Gerberding said. Congress only approved half of the $100 million requested last year to develop better flu vaccines and shore up the distribution system, she noted.
Dr. Jim Young of MedImmune said his company slashed production of its FluMist inhaled vaccine after very few people bought it last year.
"A universal recommendation that all Americans receive annual flu vaccine will drive the demand for routine annual vaccination ... which will in turn provide the impetus on the part of vaccine manufacturers to increase their production," Young told the hearing.
The vaccine is currently recommended for people over 65, infants 6 to 23 months, the chronically ill, their caregivers and pregnant women.
Crawford said the FDA was working to cut red tape. "What we are trying to do is update our processes so that we create a favorable environment for companies," he told the hearing.
© Reuters 2004. All Rights Reserved.